Protein Folding: Simple Models
نویسنده
چکیده
Doublié, S., Sawaya, M.R., and Ellenberger, T. (1999). Struct. Fold. son and Beese, 2004). The same mispair, on the other Des. 7, R31–R35. hand, is poorly extended by Dpo4: it was shown to form Echols, H., and Goodman, M.F. (1991). Annu. Rev. Biochem. 60, a reverse wobble, which misaligns the 3 -end of the 477–511. primer and therefore precludes nucleophilic attack (TrinHatahet, Z., Zhou, M., Reha-Krantz, L.J., Morrical, S.W., and Walcao et al., 2004). This example clearly illustrates that lace, S.S. (1998). Proc. Natl. Acad. Sci. USA 95, 8556–8561. molecular mechanisms, which lead to either polymerase Hogg, M., Wallace, S.S., and Doublié, S. (2004). EMBO J. 23, 1483– stalling or bypass, should be studied in the context of the 1493. DNA sequence and polymerase alike. Let the (mis)match games begin. Johnson, S.J., and Beese, L.S. (2004). Cell 116, 803–816.
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